3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats

J Med Chem. 1994 May 27;37(11):1550-2. doi: 10.1021/jm00037a002.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Acrylates / chemistry
  • Acrylates / pharmacology*
  • Alkaline Phosphatase / biosynthesis
  • Animals
  • Bone Density / drug effects
  • Bone and Bones / drug effects*
  • Cell Line
  • Cinnamates*
  • Enzyme Induction / drug effects
  • Estrogen Antagonists / pharmacology
  • Estrogens, Non-Steroidal / chemistry
  • Estrogens, Non-Steroidal / pharmacology*
  • Female
  • Humans
  • Organ Size / drug effects
  • Ovariectomy
  • Rats
  • Receptors, Estrogen / chemistry
  • Receptors, Estrogen / drug effects
  • Receptors, Estrogen / physiology
  • Stilbenes / chemistry
  • Stilbenes / pharmacology*
  • Structure-Activity Relationship
  • Uterus / anatomy & histology
  • Uterus / drug effects*
  • Uterus / enzymology

Substances

  • Acrylates
  • Cinnamates
  • Estrogen Antagonists
  • Estrogens, Non-Steroidal
  • Receptors, Estrogen
  • Stilbenes
  • 3-(4-(1,2-diphenylbut-1-enyl)phenyl)acrylic acid
  • Alkaline Phosphatase