B19 parvovirus-induced anemia in a normal child. Initial bone marrow erythroid hyperplasia and response to intravenous immunoglobulin

J C Murray; M V Gresik; F Leger; K L McClain

B19 parvovirus-induced anemia in a normal child. Initial bone marrow erythroid hyperplasia and response to intravenous immunoglobulin

Am J Pediatr Hematol Oncol. 1993 Nov;15(4):420-3.

Authors

J C Murray¹, M V Gresik, F Leger, K L McClain

Affiliation

¹ Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

PMID: 8214365

Abstract

Purpose: Human B19 parvovirus infection may cause severe erythroid hypoplasia in patients with an underlying hemolytic anemia. We report a case of severe parvovirus-induced anemia with initial marrow erythroid hyperplasia in a child with no underlying hematologic disorder.

Conclusions: The patient's rapid hemoglobin recovery after treatment with i.v. immunoglobulin further supports this form of therapy for children with parvovirus-induced anemia.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Anemia / blood
Anemia / etiology*
Anemia / pathology
Bone Marrow / pathology*
Child
Erythema Infectiosum / blood
Erythema Infectiosum / complications*
Erythema Infectiosum / pathology
Erythrocytes / drug effects
Erythrocytes / pathology*
Hematopoietic Stem Cells / pathology
Hemoglobins / metabolism
Humans
Hyperplasia
Immunoglobulins, Intravenous / therapeutic use*
Male
Parvovirus B19, Human*

Substances

Hemoglobins
Immunoglobulins, Intravenous