A spindle cell carcinoma is a rare variant of squamous cell carcinoma often presenting as a polypoid or fungating neoplasm and characterized histologically by a biphasic pattern with foci of conventional in situ or invasive squamous cell carcinoma and a fusiform cell population with a sarcomatous appearance. Most tumors of this type appear in the head and neck areas and particularly in the larynx. We have treated seven laryngeal spindle cell carcinomas in the last ten years. The object of this article is to refer their clinical presentation, biological course, histological findings, and results of treatment.