Cyclical psoriatic arthritis responding to anti-oestrogen therapy

Br J Dermatol. 1993 Oct;129(4):458-60. doi: 10.1111/j.1365-2133.1993.tb03177.x.

Abstract

We report a patient with severe psoriatic arthritis in whom the severity of both the arthritis and psoriasis fluctuated with the menstrual cycle. These features failed to improve with standard therapy, but there was a prompt response to treatment which suppressed oestrogen secretion. Such treatment should be considered in patients with disabling cyclical changes in psoriatic arthritis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthritis, Psoriatic / blood
  • Arthritis, Psoriatic / diagnostic imaging
  • Arthritis, Psoriatic / drug therapy*
  • Buserelin / therapeutic use
  • Endometrium / diagnostic imaging
  • Estradiol / blood
  • Estrogen Antagonists / therapeutic use*
  • Estrogens, Conjugated (USP) / therapeutic use
  • Female
  • Follicle Stimulating Hormone / blood
  • Goserelin / therapeutic use
  • Humans
  • Luteinizing Hormone / blood
  • Menstruation / physiology*
  • Psoriasis / blood
  • Psoriasis / diagnostic imaging
  • Psoriasis / drug therapy
  • Tamoxifen / therapeutic use
  • Ultrasonography

Substances

  • Estrogen Antagonists
  • Estrogens, Conjugated (USP)
  • Tamoxifen
  • Goserelin
  • Estradiol
  • Luteinizing Hormone
  • Follicle Stimulating Hormone
  • Buserelin