Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae

Y O Chernoff; I L Derkach; S G Inge-Vechtomov

doi:10.1007/BF00351802

Multicopy SUP35 gene induces de-novo appearance of psi-like factors in the yeast Saccharomyces cerevisiae

Curr Genet. 1993 Sep;24(3):268-70. doi: 10.1007/BF00351802.

Authors

Y O Chernoff¹, I L Derkach, S G Inge-Vechtomov

Affiliation

¹ Department of Genetics, Saint-Petersburg University, Russia.

PMID: 8221937
DOI: 10.1007/BF00351802

Abstract

Previously, we have shown that plasmid-mediated multiplication of Saccharomyces cerevisiae wild-type SUP35 gene leads to omnipotent suppression and is incompatible with psi-factor, which is an endogenous extrachromosomal suppressor. Here, we describe a frequent de-novo appearance of psi-like factors in mitotic progeny of yeast transformants containing multicopy SUP35 gene.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

DNA, Fungal
Fungal Proteins / genetics*
Genes, Fungal*
Peptide Termination Factors
Plasmids
Prions*
Saccharomyces cerevisiae / genetics*
Saccharomyces cerevisiae Proteins*
Suppression, Genetic
Transformation, Genetic

Substances

DNA, Fungal
Fungal Proteins
Peptide Termination Factors
Prions
SUP35 protein, S cerevisiae
Saccharomyces cerevisiae Proteins