Clinicopathological studies of multiple cancers in the large bowel and other organs

Kurume Med J. 1993;40(2):81-8. doi: 10.2739/kurumemedj.40.81.

Abstract

During the past 17 years, 1,463 cases of cancer of large intestine, there were 117 cases (8.0%) with overlapping cancer in other organs. The male/female ratio was 1.0:1.1 and the mean age was 65.8 years old. The region of existence in other organs was in the order of frequency: stomach 28.3%, uterus 26.3%, and liver 8.1%. The location and histology showed almost similar results to that of single cancer. In comparison with single cancer, overlapping cancer cases showed a high complication rate of adenoma. So it was suggested that a region of cancer development was present but latent. The preceding cases of cancer of the uterus almost all underwent radiotherapy. About 36% of their histology of colon cancer were mucinous carcinoma suggesting at least the development of cancer by radiation.

MeSH terms

  • Age Factors
  • Aged
  • Colonic Neoplasms / etiology
  • Colonic Neoplasms / pathology*
  • Colonic Neoplasms / therapy
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Neoplasms, Second Primary / etiology
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / therapy
  • Radiotherapy / adverse effects
  • Sex Factors
  • Treatment Outcome