[Erythroderma disclosing transformation of refractory anemia with excess of blasts into lymphoblastic leukemia]

Ann Dermatol Venereol. 1993;120(4):303-4.
[Article in French]

Abstract

We report a case of erythroderma revealing lymphoblastic leukaemia occurring immediately after myelodysplasia. The patient was an 87-year old man admitted for poor general condition, lymph node enlargement and pruriginous oedematous erythroderma. Laboratory examinations showed tricytopenia, bone marrow invasion by lymphoblasts in a myelodysplastic environment of the refractory anaemia type with excess of blasts, and a cutaneous lymphocytic infiltrate with non-blastic lymph node reaction. Owing to its morphological and immunohistological features, the lymphocytic infiltrate was regarded as non-specific. We could not help comparing this case to the other non-specific cutaneous lesions of refractory anaemia which usually reflect transformation into leukaemia.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anemia, Refractory, with Excess of Blasts / complications*
  • Cell Transformation, Neoplastic*
  • Dermatitis, Exfoliative / etiology*
  • Dermatitis, Exfoliative / pathology
  • Humans
  • Male
  • Paraneoplastic Syndromes*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology