Translocation (2;4)(p23;q25): an additional case of a new recurrent anomaly in acute myeloid leukemia

Cancer Genet Cytogenet. 1993 Oct 15;70(2):140-1. doi: 10.1016/0165-4608(93)90185-o.

Abstract

A second case of acute myeloid leukemia (AML) with a t(2;4)(p23;q25) as the sole anomaly is reported. Our case had a de novo AML (M2); the case previously described had AML (M2) post-MDS. It is suggested that t(2;4)(p23;q25) is a new, recurrent, but rare anomaly in AML.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Chromosome Banding
  • Chromosomes, Human, Pair 2*
  • Chromosomes, Human, Pair 4*
  • Cytarabine / administration & dosage
  • Daunorubicin / administration & dosage
  • Etoposide / administration & dosage
  • Female
  • Humans
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics*
  • Translocation, Genetic*

Substances

  • Cytarabine
  • Etoposide
  • Daunorubicin