Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide

Cell. 1993 Dec 17;75(6):1039-42. doi: 10.1016/0092-8674(93)90312-e.

Authors

C Haass¹, D J Selkoe

Affiliation

¹ Center for Neurologic Diseases Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts 02115.

PMID: 8261505
DOI: 10.1016/0092-8674(93)90312-e

No abstract available

Publication types

Review

MeSH terms

Alzheimer Disease / genetics
Alzheimer Disease / physiopathology*
Amino Acid Sequence
Amyloid beta-Peptides / biosynthesis
Amyloid beta-Peptides / metabolism*
Amyloid beta-Protein Precursor / genetics
Amyloid beta-Protein Precursor / metabolism*
Brain / metabolism
Cytoplasmic Granules / metabolism
Humans
Lysosomes / metabolism
Molecular Sequence Data
Protein Processing, Post-Translational*

Substances

Amyloid beta-Peptides
Amyloid beta-Protein Precursor