Bullous systemic lupus erythematosus. Report of a case with lupus erythematosus cells in the dermis

Dermatology. 1993;187(4):306-8. doi: 10.1159/000247277.

Abstract

A 20-year-old black patient with bullous systemic lupus erythematosus developed papular and vesicular lesions on the extensor surfaces of the extremities. Histologically, subepidermal blisters and papillary neutrophilic abscesses with a striking number of lupus erythematosus cells were observed. No circulating anti-basal-membrane-zone antibodies were found. By Western immunoblotting, the patient's serum showed no reactivity against epidermal or dermal extracts.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cell Nucleus / ultrastructure
  • Epidermis / pathology
  • Erythrocytes / pathology
  • Fibrin
  • Humans
  • Lupus Erythematosus, Systemic / pathology*
  • Male
  • Mucins
  • Neutrophils / pathology
  • Skin / pathology
  • Skin Diseases, Vesiculobullous / pathology*

Substances

  • Mucins
  • Fibrin