Protein-DNA assemblies controlling lytic development of bacteriophage Mu

Curr Opin Genet Dev. 1993 Oct;3(5):708-12. doi: 10.1016/s0959-437x(05)80087-5.

Abstract

Recent analysis of the mechanism and regulation of transposition by bacteriophage Mu has emphasized the importance of controlled assembly of specific protein-DNA complexes. Both the Mu transposase and the Mu repressor engage in multiple protein-protein and protein-DNA interactions that modulate the outcome of a phage infection.

Publication types

  • Review

MeSH terms

  • Bacteriolysis*
  • Bacteriophage mu / genetics
  • Bacteriophage mu / physiology*
  • DNA, Viral / metabolism*
  • Nucleotidyltransferases / genetics
  • Nucleotidyltransferases / metabolism
  • Repressor Proteins / metabolism
  • Transposases
  • Viral Proteins / metabolism*
  • Viral Regulatory and Accessory Proteins

Substances

  • DNA, Viral
  • Repressor Proteins
  • Viral Proteins
  • Viral Regulatory and Accessory Proteins
  • phage repressor proteins
  • Nucleotidyltransferases
  • Transposases