Severe idiopathic congenital aplastic anemia: role of hematopoietic growth factors

C Vermylen; G Cornu; M DeWitte; M T Heremans; J Ninane; B Brichard

Severe idiopathic congenital aplastic anemia: role of hematopoietic growth factors

Bone Marrow Transplant. 1993 Oct;12(4):413-5.

Authors

C Vermylen¹, G Cornu, M DeWitte, M T Heremans, J Ninane, B Brichard

Affiliation

¹ Department of Pediatrics, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

PMID: 8275043

Abstract

A baby boy with constitutional aplastic anemia refractory to treatment with hematopoietic growth factors underwent BMT from an unrelated HLA-compatible donor. The BM failed to engraft but the combination of a conditioning regimen, immunosuppression and hematopoietic growth factors resulted in a recovery of the patient's own BM and a good outcome.

Publication types

Case Reports

MeSH terms

Abnormalities, Multiple
Anemia, Aplastic / congenital*
Anemia, Aplastic / surgery
Anemia, Aplastic / therapy
Bone Marrow Transplantation*
Combined Modality Therapy
Drug Resistance
Granulocyte-Macrophage Colony-Stimulating Factor / therapeutic use*
Hematopoiesis
Hematopoietic Cell Growth Factors / physiology*
Humans
Immunologic Factors / therapeutic use*
Infant, Newborn
Interleukin-3 / therapeutic use*
Male

Substances

Hematopoietic Cell Growth Factors
Immunologic Factors
Interleukin-3
Granulocyte-Macrophage Colony-Stimulating Factor