Abstract
A case of esophageal small cell carcinoma with cervical node metastases and an esophago-mediastinal fistula was treated successfully by chemoradiotherapy. The fistula, after irradiation, was handled successfully by esophageal intubation, followed by infusional 5-fluorouracil and cisplatinum chemotherapy, resulting in the closure of the fistula. Two courses of concurrent chemoradiotherapy, followed by additional cisplatinum and etoposide chemotherapy, were administered. The tumor, including the cervical lymph node metastases, disappeared completely after the treatment.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Carcinoma, Small Cell / drug therapy*
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Carcinoma, Small Cell / radiotherapy*
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Carcinoma, Small Cell / secondary
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Cisplatin / administration & dosage
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Cobalt Radioisotopes / therapeutic use
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Combined Modality Therapy
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Esophageal Fistula / radiotherapy*
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Esophageal Fistula / therapy*
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Esophageal Neoplasms / drug therapy*
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Esophageal Neoplasms / radiotherapy*
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Etoposide / administration & dosage
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Fistula / radiotherapy*
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Fistula / therapy*
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Fluorouracil / administration & dosage
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Humans
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Intubation* / methods
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Lymphatic Metastasis
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Male
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Mediastinal Diseases / radiotherapy*
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Mediastinal Diseases / therapy*
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Middle Aged
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Radiotherapy Dosage
Substances
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Cobalt Radioisotopes
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Etoposide
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Cisplatin
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Fluorouracil