[Study of the structure-activity organization of the variola virus genome. II. Analysis of the nucleotide sequence of the HindIII region (C,E,R,Q,K and H)-DNA fragments of the India-1967 strain]

S N Shchelkunov; V M Blinov; S M Resenchuk; V V Gutorov; P F Safronov; R K Kurmanov; A V Totmenin; V E Chizhikov; S S Marennikova; L S Sandakhchiev

[Study of the structure-activity organization of the variola virus genome. II. Analysis of the nucleotide sequence of the HindIII region (C,E,R,Q,K and H)-DNA fragments of the India-1967 strain]

Mol Biol (Mosk). 1993 Nov-Dec;27(6):1287-303.

[Article in Russian]

Authors

S N Shchelkunov, V M Blinov, S M Resenchuk, V V Gutorov, P F Safronov, R K Kurmanov, A V Totmenin, V E Chizhikov, S S Marennikova, L S Sandakhchiev

PMID: 8283979

Abstract

Sequencing of variola virus (VAR) genome region of 43069 bp was carried out. This area contains 42 potential genes. Computer analysis of proteins coding for these viral genes was done. We compared VAR proteins with the those of vaccinia virus. The region studied is conservative for orthopoxviruses.

Publication types

English Abstract

MeSH terms

Amino Acid Sequence
DNA, Viral / genetics*
Genome, Viral*
Molecular Sequence Data
Restriction Mapping
Sequence Homology, Amino Acid
Structure-Activity Relationship
Variola virus / genetics*

Substances

DNA, Viral