Abstract
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system which predominantly affects immunologically compromised hosts. The distinctive CT appearance in three documented cases includes low-density lesions of central and convolutional white matter with scalloped lateral borders. Lesions demonstrate no mass effect or contrast material enhancement. Findings are discussed with reference to other entities which may produce a similar CT appearance.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Aged
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Brain / blood supply
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Brain Diseases / diagnostic imaging
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Central Nervous System Diseases / diagnostic imaging
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Diagnosis, Differential
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Humans
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Infarction / diagnostic imaging
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Leukoencephalopathy, Progressive Multifocal / diagnostic imaging*
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Leukoencephalopathy, Progressive Multifocal / microbiology
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Leukoencephalopathy, Progressive Multifocal / pathology
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Male
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Middle Aged
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Tomography, X-Ray Computed*