Variable pharmacodynamics of antifolates in squamous cell carcinoma of the head and neck

Adv Exp Med Biol. 1993:338:671-4. doi: 10.1007/978-1-4615-2960-6_139.

Authors

B J Braakhuis¹, G Jansen, G J Peters

Affiliation

¹ Department of Otolaryngology and Head and Neck Surgery, Free University Hospital, Amsterdam, The Netherlands.

PMID: 8304205
DOI: 10.1007/978-1-4615-2960-6_139

No abstract available

MeSH terms

Aminopterin / analogs & derivatives*
Aminopterin / metabolism
Aminopterin / toxicity
Carcinoma, Squamous Cell
Cell Division / drug effects
Cell Line
Drug Resistance
Drug Screening Assays, Antitumor / methods
Folic Acid Antagonists / toxicity*
Head and Neck Neoplasms
Humans
Methotrexate / metabolism
Methotrexate / toxicity*
Tumor Cells, Cultured

Substances

Folic Acid Antagonists
edatrexate
Aminopterin
Methotrexate