A typical case of loose anagen hair syndrome in a 4-year old girl is reported here. The key signs of this disease are the absence of hair cut since infancy, an easy and painless uprooting of the hairs and a 100 p. 100 anageneity of the hairs with distorted bulbs on trichograms. There is no known treatment of this anomaly. Cosmetically, the course of the disease is usually favourable, but abnormal trichograms and fragility of the hairs persist in adulthood. A brief review of the literature concerning this probably underestimated condition is presented.