Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. II. Physico-chemical properties and structure determination

Y Yamagishi; K Shindo; H Kawai

doi:10.7164/antibiotics.46.888

Rumbrin, a new cytoprotective substance produced by Auxarthron umbrinum. II. Physico-chemical properties and structure determination

J Antibiot (Tokyo). 1993 Jun;46(6):888-91. doi: 10.7164/antibiotics.46.888.

Authors

Y Yamagishi¹, K Shindo, H Kawai

Affiliation

¹ Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.

PMID: 8344869
DOI: 10.7164/antibiotics.46.888

Abstract

The structure of rumbrin (Fig. 1), a new cytoprotective substance, was elucidated by NMR spectral analysis. Rumbrin was found to possess a novel skeleton containing alpha-pyrone, tetraene and pyrrole moieties.

MeSH terms

Calcium Channel Blockers / chemistry*
Calcium Channel Blockers / isolation & purification
Fungi / chemistry*
Magnetic Resonance Spectroscopy
Pyrones / chemistry*
Pyrroles / chemistry*

Substances

Calcium Channel Blockers
Pyrones
Pyrroles
rumbrin