Abstract
In a study of 45 patients with anxiety disorders and 11 control subjects, mean cerebrospinal fluid (CSF) concentrations of thyrotropin-releasing hormone (TRH) were not significantly different between nonpsychiatric control subjects and those with panic disorder, generalized anxiety disorder, or obsessive-compulsive disorder. Male subjects, regardless of diagnosis, had significantly higher mean CSF concentrations of TRH than females.
Publication types
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Comparative Study
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Anxiety Disorders / diagnosis
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Anxiety Disorders / metabolism*
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Brain / metabolism
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Female
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Humans
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Male
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Neural Pathways / metabolism
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Psychiatric Status Rating Scales
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Sex Factors
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Thyrotropin-Releasing Hormone / analysis
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Thyrotropin-Releasing Hormone / cerebrospinal fluid*
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Thyrotropin-Releasing Hormone / metabolism*
Substances
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Thyrotropin-Releasing Hormone