Perturbation of the grasp component of a prehension movement in a subject with hemiParkinson's disease

Neuropsychologia. 1993 Jul;31(7):717-23. doi: 10.1016/0028-3932(93)90143-n.

Abstract

The response to perturbation of the manipulation component during prehension was assessed for both hands of a hemiParkinson and of a Control subject. With perturbed trials, the hemiParkinson showed the same pattern as the Control: a reorganization of kinematic parameters and no increase of movement time. However, for both limbs of the hemiParkinson subject there was a transition phase from precision grip to whole hand prehension--this was more pronounced for the affected limb. The manipulation component did not show a delay of activation [2]. Thus the global dysfunction in the performance of sequential movement patterns was related to aspects of task predictability.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Antiparkinson Agents / adverse effects
  • Antiparkinson Agents / therapeutic use
  • Attention / drug effects
  • Attention / physiology
  • Dominance, Cerebral / drug effects
  • Dominance, Cerebral / physiology*
  • Functional Laterality / drug effects
  • Functional Laterality / physiology
  • Humans
  • Male
  • Muscle Contraction / drug effects
  • Muscle Contraction / physiology*
  • Orientation / drug effects
  • Orientation / physiology
  • Parkinson Disease / drug therapy
  • Parkinson Disease / physiopathology*
  • Psychomotor Performance / drug effects
  • Psychomotor Performance / physiology*
  • Reaction Time / drug effects
  • Reaction Time / physiology
  • Signal Processing, Computer-Assisted

Substances

  • Antiparkinson Agents