Smoking cessation greatly reduces morbidity and mortality associated with coronary artery disease (CAD). This paper presents details of an individually delivered smoking intervention program for patients with CAD that had been shown to be effective in a previously reported randomized clinical trial. Treatment components include inpatient counseling, followed by a single outpatient visit and follow-up by telephone. This approach compared to traditional outpatient group intervention engenders much higher levels of patient participation and is suitable to the special needs of cardiac patients.