Background: Malignant mixed müllerian tumor (MMT) of tubal origin is rare and optimal therapy is unknown.
Methods: Five new cases of MMT of the fallopian tube are presented, and the previous literature is reviewed.
Results: Eight of 10 patients disease-free at 36 months had long-term cancer-free survival. Surgery alone was inadequate therapy even for those with apparent Stage I disease. Five of six treated postoperatively with radiation and chemotherapy have lived disease-free for at least 45 months.
Conclusions: Combination radiation and chemotherapy may offer improved outcome.