Reye syndrome associated with subclinical varicella zoster virus and influenza A infection

Pediatr Neurol. 1993 Mar-Apr;9(2):134-6. doi: 10.1016/0887-8994(93)90050-m.

Abstract

An association is reported between Reye syndrome and varicella zoster virus (VZV) infection in a 10-year-old boy who had serologic evidence of coinfection with VZV and influenza A H3N2, and exposure to salicylates. He developed VZV reinfection without skin lesions after family exposure and influenza A was community-acquired. Recent chickenpox contact should initiate VZV serologic studies in Reye syndrome patients, regardless of the chickenpox history or evidence of infection with other viruses.

Publication types

  • Case Reports

MeSH terms

  • Amino Acids / blood
  • Ammonia / blood
  • Antibodies, Viral / blood
  • Aspirin / administration & dosage
  • Aspirin / adverse effects
  • Child
  • Herpes Zoster / diagnosis*
  • Herpes Zoster / drug therapy
  • Herpesvirus 3, Human / immunology
  • Humans
  • Influenza A virus* / immunology
  • Influenza A virus* / isolation & purification
  • Influenza, Human / diagnosis*
  • Influenza, Human / drug therapy
  • Liver Function Tests
  • Male
  • Neurologic Examination / drug effects
  • Reye Syndrome / chemically induced
  • Reye Syndrome / diagnosis*

Substances

  • Amino Acids
  • Antibodies, Viral
  • Ammonia
  • Aspirin