Combined anti-fungal therapy and surgical resection as treatment of disseminated aspergillosis of the lung and brain following BMT

M E Trigg; A H Menezes; R Giller; L Lanza; R J Smith; Y Sato; C Peters; A Altman

Combined anti-fungal therapy and surgical resection as treatment of disseminated aspergillosis of the lung and brain following BMT

Bone Marrow Transplant. 1993 Jun;11(6):493-6.

Authors

M E Trigg¹, A H Menezes, R Giller, L Lanza, R J Smith, Y Sato, C Peters, A Altman

Affiliation

¹ Department of Pediatrics, University of Iowa Hospitals and Clinics, Iowa City 52242.

PMID: 8392887

Abstract

This report describes a 6-year-old girl with pre-B ALL who developed systemic aspergillosis following BMT. She was successfully treated with a combination of amphotericin B, itraconazole and surgery. This report emphasizes the importance of surgical resection in the management of disseminated aspergillosis.

Publication types

Case Reports

MeSH terms

Amphotericin B / therapeutic use*
Antifungal Agents / therapeutic use*
Aspergillosis / diagnostic imaging
Aspergillosis / drug therapy
Aspergillosis / microbiology
Aspergillosis / surgery*
Bone Marrow Transplantation*
Child
Female
Humans
Itraconazole
Ketoconazole / analogs & derivatives*
Ketoconazole / therapeutic use
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Tomography, X-Ray Computed

Substances

Antifungal Agents
Itraconazole
Amphotericin B
Ketoconazole