Primary structure of the mouse beta 1-adrenergic receptor gene

Biochim Biophys Acta. 1993 Sep 13;1178(3):307-9. doi: 10.1016/0167-4889(93)90209-8.

Abstract

The mouse beta 1-adrenergic receptor was isolated from a genomic library and cloned into pBluescript SK-. Characterization of the clone revealed an open reading frame which encodes a predicted protein of 466 amino acids. The mouse beta 1 receptor is 92.7% identical to the human sequence, 98.5% identical to the rat sequence, and contains a consensus site for N-linked glycosylation at Asn-15 and a cAMP-dependent protein kinase phosphorylation site at Ser-301.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Binding Sites
  • Cloning, Molecular
  • Mice
  • Molecular Sequence Data
  • Plasmids
  • Receptors, Adrenergic, beta / chemistry
  • Receptors, Adrenergic, beta / genetics*
  • Receptors, Adrenergic, beta / isolation & purification

Substances

  • Receptors, Adrenergic, beta

Associated data

  • GENBANK/L08435
  • GENBANK/L08436
  • GENBANK/L08437
  • GENBANK/L08438
  • GENBANK/L08439
  • GENBANK/L08440
  • GENBANK/L08441
  • GENBANK/L08442
  • GENBANK/L08443
  • GENBANK/L10084