Abstract
C-terminal truncations of the human T-cell leukemia virus type I envelope affected the intracellular maturation and syncytium formation in a cell type-dependent manner. The intracytoplasmic domain appears dispensable for syncytium formation, but its truncation can modulate the envelope functionality in some cell types.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line / microbiology
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DNA Mutational Analysis
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Gene Products, env / genetics*
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Genetic Variation
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Human T-lymphotropic virus 1 / genetics*
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Humans
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Protein Conformation
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Retroviridae Proteins, Oncogenic / genetics*
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Transfection
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Viral Envelope Proteins / genetics*
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Viral Fusion Proteins / genetics*
Substances
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Gene Products, env
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Retroviridae Proteins, Oncogenic
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Viral Envelope Proteins
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Viral Fusion Proteins
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gp46 protein, Human T-cell leukemia virus type I
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transmembrane envelope glycoprotein gp45, retrovirus