Abstract
Rhodobacter sphaeroides showed chemotaxis towards L-alanine but not towards the analog 2-aminoisobutyrate. 2-Aminoisobutyrate and alanine were shown to share a common transport system, but 2-aminoisobutyrate was not metabolized. Chemotaxis towards alanine was inhibited by structurally unrelated metabolites, suggesting cross-inhibition by common metabolic intermediates.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Alanine / metabolism*
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Alanine / pharmacology
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Aminoisobutyric Acids / metabolism*
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Aminoisobutyric Acids / pharmacology
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Biological Transport
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Carbon Dioxide / metabolism
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Carbonyl Cyanide m-Chlorophenyl Hydrazone / pharmacology
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Cell Communication*
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Chemotaxis / physiology*
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Dose-Response Relationship, Drug
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Rhodobacter sphaeroides / drug effects
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Rhodobacter sphaeroides / metabolism*
Substances
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Aminoisobutyric Acids
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Carbon Dioxide
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2-aminoisobutyric acid
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Carbonyl Cyanide m-Chlorophenyl Hydrazone
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Alanine