Decreased IFN-gamma and IL-2 mRNA expression in peripheral tolerance to heart allografts with conserved granzyme A, perforin, and MHC antigens mRNA expression

Transplant Proc. 1993 Feb;25(1 Pt 1):314-6.

Authors

L Bugeon¹, M C Cuturi, J Paineau, D Chabannes, J P Soulillou

Affiliation

¹ Institut National de la Santé et la Recherche Médicale (INSERM U211), Nantes, France.

PMID: 8438315

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blood Transfusion
Graft Rejection / immunology
Graft Survival / immunology
Granzymes
Heart Transplantation / immunology*
Histocompatibility Antigens / biosynthesis*
Histocompatibility Antigens / genetics
Immune Tolerance*
Interferon-gamma / biosynthesis*
Interferon-gamma / genetics
Interleukin-2 / biosynthesis*
Interleukin-2 / genetics
Major Histocompatibility Complex*
Membrane Glycoproteins / biosynthesis*
Membrane Glycoproteins / genetics
Perforin
Pore Forming Cytotoxic Proteins
RNA, Messenger / biosynthesis*
Rats
Rats, Inbred Lew
Serine Endopeptidases / biosynthesis*
Serine Endopeptidases / genetics
T-Lymphocytes, Cytotoxic / immunology
Transplantation, Heterotopic
Transplantation, Homologous / immunology

Substances

Histocompatibility Antigens
Interleukin-2
Membrane Glycoproteins
Pore Forming Cytotoxic Proteins
RNA, Messenger
Perforin
Interferon-gamma
Granzymes
Serine Endopeptidases