Clozapine-lithium combined treatment and agranulocytosis

Int Clin Psychopharmacol. 1993 Spring;8(1):63-5. doi: 10.1097/00004850-199300810-00011.

Abstract

A case report of clozapine-induced agranulocytosis in a patient treated concomitantly with lithium is reported. The possible role of lithium in the mechanism of clozapine myelosuppression is discussed.

Publication types

  • Case Reports

MeSH terms

  • Agranulocytosis / chemically induced*
  • Clozapine / adverse effects
  • Clozapine / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Granulocytes / drug effects
  • Humans
  • Leukocyte Count / drug effects
  • Lithium / therapeutic use*
  • Middle Aged
  • Psychotic Disorders / drug therapy
  • Time Factors

Substances

  • Lithium
  • Clozapine