Omeprazole induction of cytochrome P-450IA2: the importance of selecting the appropriate human model

Hepatology. 1993 Apr;17(4):748-50. doi: 10.1002/hep.1840170432.
No abstract available

MeSH terms

  • Animals
  • Cells, Cultured
  • Cytochrome P-450 CYP1A2
  • Cytochrome P-450 Enzyme System / biosynthesis*
  • Enzyme Induction
  • Humans
  • Liver / drug effects
  • Liver / enzymology*
  • Models, Biological
  • Omeprazole / pharmacology*
  • Oxidoreductases / biosynthesis*
  • Rabbits
  • Rats

Substances

  • Cytochrome P-450 Enzyme System
  • Oxidoreductases
  • Cytochrome P-450 CYP1A2
  • Omeprazole