RNA polymerase II transcription cycles

Curr Opin Genet Dev. 1993 Apr;3(2):213-8. doi: 10.1016/0959-437x(93)90025-k.

Abstract

RNA polymerase II interacts with transcription factors to initiate the synthesis of mRNA. These interactions are cyclic, involving multiple RNA polymerase subunits and general transcription factors. Phosphorylation of the RNA polymerase II carboxyl-terminal domain may regulate these interactions.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Gene Expression Regulation
  • Molecular Sequence Data
  • Phosphorylation
  • Promoter Regions, Genetic
  • Protein Binding
  • Protein Processing, Post-Translational
  • RNA Polymerase II / metabolism*
  • Sigma Factor / physiology
  • Transcription Factors / physiology
  • Transcription, Genetic*

Substances

  • Sigma Factor
  • Transcription Factors
  • RNA Polymerase II