[A case report: multiple liver metastasis of gastric cancer responding to intraarterial infusion of MTX and 5-FU]

Gan To Kagaku Ryoho. 1993 Jun;20(8):1055-7.
[Article in Japanese]

Abstract

In a 63-year-old male patient with gastric cancer having multiple liver metastases, the metastatic lesions responded well to postoperative staggered intraarterial infusion therapy with MTX and 5-FU. The intraarterial infusion therapy was administered once a week. A total of 5 courses of this therapy produced marked regression of liver metastases and remarkable necrosis. The effect was thus rated as PR. The patient is healthy and has been successfully rehabilitated. His dose is oral 5-FU (200 mg x 2).

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / secondary*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Drug Administration Schedule
  • Fluorouracil / administration & dosage
  • Gastrectomy
  • Humans
  • Infusions, Intra-Arterial
  • Leucovorin / administration & dosage
  • Liver Neoplasms / drug therapy*
  • Liver Neoplasms / secondary*
  • Male
  • Methotrexate / administration & dosage
  • Middle Aged
  • Remission Induction
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / surgery

Substances

  • Leucovorin
  • Fluorouracil
  • Methotrexate