[Clear-cell sarcoma of the tendons and aponeuroses. Immunohistochemical study of 2 cases]

Pathologica. 1995 Apr;87(2):142-5.
[Article in Italian]

Abstract

Two cases of clear cell sarcoma of tendons and aponeuroses are reported. Clinical setting, protracted course, and light microscopic appearance were in a agreement with the original description. In the first case the tumor required differential diagnosis from metastatic malignant melanoma because of the lack of the overlying skin and of the epithelial histological pattern. In the second case diagnosis was not too difficult; the tumor consisted of nest or fascicles of uniform pale staining cells intermingled by inconspicuous multinucleated giant cells with peripherally placed nuclei. The histologic features and immunohistochemistry are also discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antibodies, Monoclonal / immunology
  • Biomarkers, Tumor / analysis*
  • Diagnosis, Differential
  • Extracellular Matrix Proteins / analysis
  • Giant Cells / pathology
  • Humans
  • Immunoenzyme Techniques
  • Leg
  • Male
  • Melanoma / diagnosis
  • Middle Aged
  • Neoplasm Proteins / analysis*
  • Nerve Tissue Proteins / analysis
  • Sarcoma / chemistry
  • Sarcoma / diagnosis
  • Sarcoma / pathology*
  • Sarcoma, Clear Cell / chemistry
  • Sarcoma, Clear Cell / diagnosis
  • Sarcoma, Clear Cell / pathology*
  • Tendons*

Substances

  • Antibodies, Monoclonal
  • Biomarkers, Tumor
  • Extracellular Matrix Proteins
  • Neoplasm Proteins
  • Nerve Tissue Proteins