Abstract
From Isodon gesneroides, three new cytotoxic diterpenoids, gesneroidins A, B and C, together with one known diterpenoid, dawoensin A, were isolated, and the structure determination and unambiguous assignment of their stereochemistry and NMR spectral data were made by a combination of one-and two-dimensional NMR techniques, computer modelling calculations and X-ray analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / isolation & purification*
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Anti-Infective Agents / toxicity
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Anti-Inflammatory Agents / chemistry
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Anti-Inflammatory Agents / isolation & purification*
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Anti-Inflammatory Agents / toxicity
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Computer Simulation
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Crystallography, X-Ray
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Diterpenes / chemistry
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Diterpenes / isolation & purification*
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Diterpenes / toxicity
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Magnetic Resonance Spectroscopy / methods
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Mass Spectrometry
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Molecular Structure
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Plants, Medicinal / chemistry*
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Stereoisomerism
Substances
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Anti-Infective Agents
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Anti-Inflammatory Agents
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Diterpenes