Successful pregnancy following aplastic anaemia

Postgrad Med J. 1995 Oct;71(840):625-7. doi: 10.1136/pgmj.71.840.625.

Abstract

Pregnancy following idiopathic aplastic anaemia is rare and is difficult to manage because of life-threatening episodes of bleeding and infections. Only a handful of cases has been reported in the literature. The pregnancies were unsuccessful in the majority. The present report describes a patient with moderately severe idiopathic aplastic anaemia who was managed with intensive haematological support leading to delivery of a healthy infant by caesarean section. Despite platelet transfusion refractoriness as a result of transfusions prior to pregnancy, adequate platelet transfusions prevented excessive bleeding. The literature is reviewed and management with platelet transfusions is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Aplastic / etiology
  • Anemia, Aplastic / therapy*
  • Female
  • Humans
  • Platelet Transfusion
  • Pregnancy Complications, Hematologic / etiology*
  • Pregnancy Complications, Hematologic / therapy
  • Pregnancy*