Abstract
The relationship between the degree of nocturnal oxygen desaturation (NOD) and pulmonary hemodynamics, pulmonary function tests, and resting awake blood gases was evaluated in patients with chronic pulmonary diseases (CPD). The severity of NOD correlated with the degree of impairment of pulmonary hemodynamics, but not with pulmonary function tests or resting awake blood gases. NOD was markedly alleviated by oxygen inhalation in CPD patients who did not develop sleep apnea.
MeSH terms
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Aged
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Bronchitis / blood
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Bronchitis / physiopathology
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Carbon Dioxide / blood
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Circadian Rhythm
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Female
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Forced Expiratory Volume
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Humans
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Hypoxia / blood*
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Hypoxia / physiopathology
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Hypoxia / therapy
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Lung Diseases, Obstructive / blood*
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Lung Diseases, Obstructive / physiopathology
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Male
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Middle Aged
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Monitoring, Physiologic / instrumentation*
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Oximetry / instrumentation*
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Oxygen / blood*
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Oxygen Inhalation Therapy
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Pulmonary Emphysema / blood
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Pulmonary Emphysema / physiopathology
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Pulmonary Fibrosis / blood
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Pulmonary Fibrosis / physiopathology
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Pulmonary Wedge Pressure
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Rest
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Sleep Apnea Syndromes / blood*
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Vascular Resistance
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Ventilation-Perfusion Ratio
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Vital Capacity
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Wakefulness