Abstract
Substantial progress has been reported in the treatment of patients with alcoholism in the United States. Studies that seek to identify the most appropriate form of therapy for alcohol-dependent patients have been an important part of this effort. Recognition that psychotherapy alone cannot help all patients who have alcoholism has led to interest in the use of pharmacotherapy. Recent research demonstrates that pharmacotherapy with the opioid receptor antagonists naltrexone and nalmefene helps prevent relapse in many alcohol-dependent patients.
Publication types
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Clinical Trial
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Comparative Study
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Randomized Controlled Trial
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Alcoholics Anonymous
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Alcoholism / psychology
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Alcoholism / rehabilitation*
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Cognitive Behavioral Therapy
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Combined Modality Therapy
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Dose-Response Relationship, Drug
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Drug Administration Schedule
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Humans
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Naltrexone / adverse effects
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Naltrexone / analogs & derivatives*
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Naltrexone / therapeutic use*
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Narcotic Antagonists / adverse effects
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Narcotic Antagonists / therapeutic use*
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Treatment Outcome
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United States
Substances
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Narcotic Antagonists
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Naltrexone
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nalmefene