Co-localization of mu-opioid receptor-like and substance P-like immunoreactivities in axon terminals within the superficial layers of the medullary and spinal dorsal horns of the rat

Y Q Ding; S Nomura; T Kaneko; N Mizuno

doi:10.1016/0304-3940(95)11960-5

Co-localization of mu-opioid receptor-like and substance P-like immunoreactivities in axon terminals within the superficial layers of the medullary and spinal dorsal horns of the rat

Neurosci Lett. 1995 Sep 22;198(1):45-8. doi: 10.1016/0304-3940(95)11960-5.

Authors

Y Q Ding¹, S Nomura, T Kaneko, N Mizuno

Affiliation

¹ Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan.

PMID: 8570093
DOI: 10.1016/0304-3940(95)11960-5

Abstract

The presence of mu-opioid receptor-like immunoreactivity (MOR-LI) on axon terminals was confirmed by light and electron microscopy within the superficial layers of the medullary and spinal dorsal horns of the rat. By means of double-immunofluorescence histochemistry, co-localization of MOR-LI and substance P (SP)-LI was occasionally observed in axon terminals within the superficial layers of the dorsal horns.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Immunoglobulin G / immunology
Immunohistochemistry
Medulla Oblongata / cytology
Medulla Oblongata / metabolism*
Microscopy, Confocal
Microscopy, Electron
Nerve Fibers / metabolism
Presynaptic Terminals / metabolism*
Rats
Rats, Wistar
Receptors, Opioid, mu / metabolism*
Spinal Cord / cytology
Spinal Cord / metabolism*
Substance P / metabolism*

Substances

Immunoglobulin G
Receptors, Opioid, mu
Substance P