The authors report the case of a 33-year-old right-handed man who developed a pure classical amnesic syndrome during the course of a probable tuberculous meningitis. This amnesic syndrome occurred 3 months after the onset of the illness, after the patient had stopped the treatment and it regressed completely after the antituberculous treatment had been recommenced. The neuroradiological investigations suggested that both the mamillary bodies and the medial temporal lobe regions were involved in this amnesic syndrome.