Two maternally derived missense mutations in the tyrosine kinase domain of the RET protooncogene in a patient with de novo MEN 2B

Hum Mol Genet. 1995 Oct;4(10):1987-8. doi: 10.1093/hmg/4.10.1987.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Base Sequence
  • DNA Primers
  • Deoxyribonucleases, Type II Site-Specific
  • Drosophila Proteins*
  • Female
  • Humans
  • Male
  • Molecular Sequence Data
  • Multiple Endocrine Neoplasia Type 2b / genetics*
  • Pedigree
  • Point Mutation*
  • Polymerase Chain Reaction
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-ret
  • Proto-Oncogenes*
  • Receptor Protein-Tyrosine Kinases / genetics*
  • Restriction Mapping

Substances

  • DNA Primers
  • Drosophila Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-ret
  • Receptor Protein-Tyrosine Kinases
  • Ret protein, Drosophila
  • endodeoxyribonuclease FokI
  • Deoxyribonucleases, Type II Site-Specific