Detection of BRCA1 mutations by the protein truncation test

Hum Mol Genet. 1995 Oct;4(10):1989-91. doi: 10.1093/hmg/4.10.1989.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Age of Onset
  • BRCA1 Protein
  • Base Sequence
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 17*
  • DNA Primers
  • Exons
  • Family
  • Female
  • Humans
  • Molecular Sequence Data
  • Neoplasm Proteins / biosynthesis
  • Neoplasm Proteins / genetics*
  • Neoplasms, Multiple Primary / genetics
  • Ovarian Neoplasms / epidemiology
  • Ovarian Neoplasms / genetics*
  • Point Mutation*
  • Polymerase Chain Reaction
  • Protein Biosynthesis
  • Serine
  • Transcription Factors / biosynthesis
  • Transcription Factors / genetics*
  • Transcription, Genetic

Substances

  • BRCA1 Protein
  • DNA Primers
  • Neoplasm Proteins
  • Transcription Factors
  • Serine