Trigeminoparabrachial projection neurons showing substance P receptor-like immunoreactivity in the rat

Neurosci Res. 1995 Nov;23(4):415-8. doi: 10.1016/0168-0102(95)00961-R.

Abstract

By means of substance P receptor (SPR) immunofluorescence histochemistry combined with Fluoro-Gold fluorescent retrograde labeling, SPR-like immunoreactive neurons in the caudal subnucleus of the spinal trigeminal nucleus of the rat were observed to send their axons to the nucleus of Kölliker-Fuse and ventrolateral part of the lateral parabrachial nucleus bilaterally with a clear ipsilateral dominance. These neurons were distributed mainly in lamina I, and additionally in lamina III.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibody Specificity
  • Fluorescent Antibody Technique
  • Male
  • Neurons / chemistry*
  • Neurons / immunology
  • Neurons, Afferent / chemistry
  • Neurons, Afferent / immunology
  • Nociceptors / physiology
  • Rats
  • Rats, Wistar
  • Receptors, Neurokinin-1 / immunology*
  • Substance P / analysis
  • Substance P / immunology
  • Trigeminal Caudal Nucleus / chemistry*
  • Trigeminal Caudal Nucleus / cytology

Substances

  • Receptors, Neurokinin-1
  • Substance P