35 patients (11 men, 24 women, aged 5-73) with mesenchymal tumor of mediastinum were surgically treated in the period 1970-1993. This group stated 10,3% of all patients treated because of cysts and tumors of mediastinum in this time. In 17 cases tumors were benign and in 18 malignant. In 31 pts total resection and in 3-partial resection were done. 5 out of 15 pts with malignant tumor are alive.