[Mixed carcinoid-carcinoma of the stomach]

Cesk Patol. 1995 Dec;31(4):135-8.
[Article in Czech]

Abstract

Bioptical observation of a mixed carcinoid-carcinoma in a 75-year-old man's stomach was described. The subcardial tumour was 10-7 cm in diameter with secondaries in perigastric lymph nodes. A well differentiated adenocarcinoma with mucus production formed a minor marginal part of the carcinoid which expressed immunohistochemical markers common in gut cancers: carcinoembryonic antigen, epithelial membrane antigen and some cytokeratins. The well differentiated adenocarcinoma expressed different cytokeratins detected by AE1-AE3 antibody. The carcinoid was positive with Grimelius impregnation and strongly positive with chromogranin A and synaptophysin bound antibodies. Transition of both the tumour types was continuous.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / pathology*
  • Aged
  • Carcinoid Tumor / chemistry
  • Carcinoid Tumor / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Stomach Neoplasms / chemistry
  • Stomach Neoplasms / pathology*