Abstract
Febrile neutropenic children with cancer were eligible for outpatient management with intravenous ceftriaxone therapy if they displayed selected low-risk criteria. Nineteen children were enrolled. All patients had sterile blood cultures, and only one of them was hospitalized because of persistent fever. This pilot study suggests that selected children with febrile neutropenia might be successfully managed without hospitalization.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Ambulatory Care
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bacteremia / drug therapy*
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Bacteremia / etiology
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Ceftriaxone / adverse effects
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Ceftriaxone / therapeutic use*
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Cephalosporins / adverse effects
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Cephalosporins / therapeutic use*
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Child
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Child, Preschool
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Female
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Fever of Unknown Origin / drug therapy*
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Fever of Unknown Origin / etiology
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Humans
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Infant
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Infusions, Intravenous
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Leukocyte Count / drug effects
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Male
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Neoplasms / drug therapy*
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Neutropenia / chemically induced*
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Neutropenia / drug therapy
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Neutrophils / drug effects
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Platelet Count / drug effects
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Treatment Outcome
Substances
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Cephalosporins
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Ceftriaxone