Authors report a case with photorefractive retreatment after previous radial keratotomy (RK) due to a -4.5 D refractive error. The indication of retreatment was a -2.75 D regression during the one-year follow-up time after RK. The photorefractive keratectomy (PRK) was performed with the Aesculap Meditec MEL 60 excimer laser. During the 8-month follow-up time, in the retreated eye the uncorrected visual acuity was fully recovered, no regression was experienced. The excimer laser appears to be a good method to correct refractive errors, regressed or retained from previous refractive procedures due to the possibility of precise calibrating and the moderate ablation depth compared to the total thickness of the cornea.