Abstract
This manuscript reports the differential expression of the AF4 gene among human tissues. AF4 mRNA is highly expressed in normal placental tissue which correlates with the newborn age of patients presenting with leukemia characterized by the MLL/AF4 gene rearrangement.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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Blotting, Northern
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DNA, Complementary
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DNA-Binding Proteins / genetics*
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Gene Expression
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Humans
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Molecular Sequence Data
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Nuclear Proteins / genetics*
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Placenta / metabolism
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RNA, Messenger
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Tissue Distribution
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Transcriptional Elongation Factors
Substances
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DNA, Complementary
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DNA-Binding Proteins
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Nuclear Proteins
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RNA, Messenger
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Transcriptional Elongation Factors
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AFF1 protein, human