[Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists]

Bull Cancer Radiother. 1996;83(2):86-9.
[Article in French]

Abstract

From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Actuarial Analysis
  • Adult
  • Aged
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / radiotherapy*
  • Carcinoma, Squamous Cell / surgery
  • Combined Modality Therapy
  • Female
  • Humans
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / radiotherapy*
  • Laryngeal Neoplasms / surgery
  • Lymphatic Irradiation*
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neck
  • Pharyngeal Neoplasms / pathology
  • Pharyngeal Neoplasms / radiotherapy*
  • Pharyngeal Neoplasms / surgery
  • Postoperative Period
  • Radiotherapy Dosage
  • Retrospective Studies
  • Survival Analysis