Collapse and cooperativity in protein folding

Curr Opin Struct Biol. 1996 Feb;6(1):31-42. doi: 10.1016/s0959-440x(96)80092-3.

Abstract

The folding of a polypeptide chain is associated both with compactness and cooperativity within local and global regions of the protein structure, and with the formation of the native-like molecular architecture. Recent experiments shed light on these issues and their relationships to the pathways of protein folding.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Proteins / chemistry
  • Bacterial Proteins / physiology
  • Chemical Phenomena
  • Chemistry, Physical
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Molecular Chaperones / physiology
  • Protein Conformation
  • Protein Folding*
  • Scattering, Radiation

Substances

  • Bacterial Proteins
  • Molecular Chaperones