Abstract
Five new prenylflavones, yinyanghuo A (1), yinyanghuo B (2), yinyanghuo C (3), yinyanghuo D (4), and yinyanghuo E (5), along with six known flavonoids, chrysoeriol, quercetin, apigenin, apigenin 7,4'-dimethyl ether, kaempferol, and luteolin, were isolated from the leaves of Epimedium sagittatum. Their structures were determined from spectral analysis. Compounds 1 and 2 showed significant antiplatelet induced by arachidonic acid.
MeSH terms
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Arachidonic Acid / antagonists & inhibitors
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Arachidonic Acid / pharmacology
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Flavonoids / isolation & purification*
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Flavonoids / pharmacology
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In Vitro Techniques
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Nephelometry and Turbidimetry
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Plants, Medicinal / chemistry*
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Platelet Aggregation / drug effects
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Platelet Aggregation Inhibitors / isolation & purification*
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Platelet Aggregation Inhibitors / pharmacology
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Taiwan
Substances
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Flavonoids
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Platelet Aggregation Inhibitors
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Arachidonic Acid